A Simple Protocol for Direct Reductive Amination of Aldehydes and Ketones Using Potassium Formate and Catalytic Palladium Acetate
Date
2012-11-21
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Abstract
A method for direct reductive amination of aldehydes
and ketones, including á,â-unsaturated carbonyl compounds, has
been developed, which requires potassium formate as reductant and
palladium acetate as catalyst. Suitable amines include both primary
and secondary aliphatic and aromatic amines.
Description
A method for direct reductive amination of aldehydes
and ketones, including a,ß-unsaturated carbonyl compounds, has
been developed, which requires potassium formate as reductant and
palladium acetate as catalyst. Suitable amines include both primary
and secondary aliphatic and aromatic amines
Keywords
reductive amination, potassium formate, palladium acetate, one-pot reaction