Sosale ChandrasekharMalayalam Sridhar2012-11-202025-02-172012-11-202012-11-20https://dl.ftveti.edu.et/handle/123456789/4219A novel sonication-promoted Barbier reaction putatively generated the titled species from the corre- sponding naphthotriazinylmethyl chloride and magnesium in THF: its formal addition to a variety of carbonyl compounds in situ occurred in excellent yields. Subsequent catalytic hydrogenolysis of the triazine moiety demasked the amine, thus de®ning a route to various phenylethylamines (including the alkaloid `mescaline'), or ethanolamines (in two cases), in excellent overall yields. # 2000 Elsevier Science Ltd. All rights reserved.A novel sonication-promoted Barbier reaction putatively generated the titled species from the corre- sponding naphthotriazinylmethyl chloride and magnesium in THF: its formal addition to a variety of carbonyl compounds in situ occurred in excellent yields. Subsequent catalytic hydrogenolysis of the triazine moiety demasked the amine, thus de®ning a route to various phenylethylamines (including the alkaloid `mescaline'), or ethanolamines (in two cases), in excellent overall yields. # 2000 Elsevier Science Ltd. All rights reserved.enKeywords: alkaloids; a-aminomethyl carbanion; Barbier reaction; mescaline; naphthotriazine; phenylethylamine; ultra- sounArticle