BEVERLY A[ CLEMENTCHRISTINA M[ GOFFT[ DAVID A[ FORBES2012-11-142025-02-172012-11-142012-11-14https://dl.ftveti.edu.et/handle/123456789/4047Acacia ri`idula Benth[\ blackbrush\ is a shrub found growing on rocky ridges in west and southwest Texas and northern Mexico[ Consumption of blackbrush and a related species guajillo\ Acacia berlandieri Benth[\ has been associated with a locomotor ataxia known as {{limber leg||[ In an e}ort to identify the mechanism of this toxicity\ blackbrush was subjected to rigorous chemical analysis[ In addition to the four previously detected amines\N!methyl!b!phenethylamine\ tyramine\N!methyltyramine\ and hordenine\ 39 other alkaloids and amines were isolated and identi_ed by GC!MS[ These alkaloids and amines included nicotine\ N\N!dimethyltryptamine\ mescaline\ several tetrahydroisoquinoline alkaloids\ and four amphetamines[ A sig! ni_cant increase in the number and relative quantities of these compounds was observed in late season foliage[ 0887 Elsevier Science Ltd[ All rights reservedAcacia ri`idula Benth[\ blackbrush\ is a shrub found growing on rocky ridges in west and southwest Texas and northern Mexico[ Consumption of blackbrush and a related species guajillo\ Acacia berlandieri Benth[\ has been associated with a locomotor ataxia known as {{limber leg||[ In an e}ort to identify the mechanism of this toxicity\ blackbrush was subjected to rigorous chemical analysis[ In addition to the four previously detected amines\N!methyl!b!phenethylamine\ tyramine\N!methyltyramine\ and hordenine\ 39 other alkaloids and amines were isolated and identi_ed by GC!MS[ These alkaloids and amines included nicotine\ N\N!dimethyltryptamine\ mescaline\ several tetrahydroisoquinoline alkaloids\ and four amphetamines[ A sig! ni_cant increase in the number and relative quantities of these compounds was observed in late season foliage[ 0887 Elsevier Science Ltd[ All rights reservedenAcacia ri`udula^ blackbrush^ Leguminosae^ alkaloids^ GC:MS[Article