An a-aminomethyl carbanion equivalent via a novel Barbier reaction: (1H-naphtho[1,8-de]-1,2,3-triazin-2-yl)methyl anion
| dc.contributor.author | Sosale Chandrasekhar | |
| dc.contributor.author | Malayalam Sridhar | |
| dc.date.accessioned | 2012-11-20T13:06:00Z | |
| dc.date.accessioned | 2025-02-17T14:02:05Z | |
| dc.date.available | 2012-11-20T13:06:00Z | |
| dc.date.issued | 2012-11-20 | |
| dc.description | A novel sonication-promoted Barbier reaction putatively generated the titled species from the corre- sponding naphthotriazinylmethyl chloride and magnesium in THF: its formal addition to a variety of carbonyl compounds in situ occurred in excellent yields. Subsequent catalytic hydrogenolysis of the triazine moiety demasked the amine, thus de®ning a route to various phenylethylamines (including the alkaloid `mescaline'), or ethanolamines (in two cases), in excellent overall yields. # 2000 Elsevier Science Ltd. All rights reserved. | en_US |
| dc.description.abstract | A novel sonication-promoted Barbier reaction putatively generated the titled species from the corre- sponding naphthotriazinylmethyl chloride and magnesium in THF: its formal addition to a variety of carbonyl compounds in situ occurred in excellent yields. Subsequent catalytic hydrogenolysis of the triazine moiety demasked the amine, thus de®ning a route to various phenylethylamines (including the alkaloid `mescaline'), or ethanolamines (in two cases), in excellent overall yields. # 2000 Elsevier Science Ltd. All rights reserved. | en_US |
| dc.identifier.uri | https://dl.ftveti.edu.et/handle/123456789/4219 | |
| dc.language.iso | en | en_US |
| dc.subject | Keywords: alkaloids; a-aminomethyl carbanion; Barbier reaction; mescaline; naphthotriazine; phenylethylamine; ultra- soun | en_US |
| dc.title | An a-aminomethyl carbanion equivalent via a novel Barbier reaction: (1H-naphtho[1,8-de]-1,2,3-triazin-2-yl)methyl anion | en_US |
| dc.type | Article | en_US |
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