Stereospecific synthesis of amphetamines

dc.contributor.author	Jared M. Wagner
dc.contributor.author	Charles J. McElhinny
dc.contributor.author	Jr.Anita H. Lewin
dc.contributor.author	F. Ivy Carroll
dc.date.accessioned	2012-11-20T09:23:07Z
dc.date.accessioned	2025-02-17T14:01:42Z
dc.date.available	2012-11-20T09:23:07Z
dc.date.issued	2012-11-20
dc.description	Regioselective addition of aryl lithium to commercially available (S)-(+)-propylene oxide provides the corresponding (S)-aryl-2-propanol. The (R)-amphetamine is obtained by conversion of the alcohol to the tosylate followed by azide displacement and hydrogenation. Mitsunobu conversion of the alcohol to the (R)-bromide followed by azide displacement and hydrogenation affords the (S)-amphetamine. © 2003 Elsevier Ltd. All rights reserved	en_US
dc.description.abstract	Regioselective addition of aryl lithium to commercially available (S)-(+)-propylene oxide provides the corresponding (S)-aryl-2-propanol. The (R)-amphetamine is obtained by conversion of the alcohol to the tosylate followed by azide displacement and hydrogenation. Mitsunobu conversion of the alcohol to the (R)-bromide followed by azide displacement and hydrogenation affords the (S)-amphetamine. © 2003 Elsevier Ltd. All rights reserved	en_US
dc.identifier.uri	https://dl.ftveti.edu.et/handle/123456789/4162
dc.language.iso	en	en_US
dc.subject	Stereospecific synthesis of amphetamines	en_US
dc.title	Stereospecific synthesis of amphetamines	en_US
dc.type	Article	en_US

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