Solid-Phase Synthesis of 2,3-Disubstituted Indoles: Discovery of a Novel, High-A nity, Selective h5-HT2A Antagonist

Abstract

The application of a novel solid-phase synthesis of 2,3-disubstituted indoles utilizing a carbamate indole linker is described resulting in the identi®cation of the novel, high-a nity, selective h5-HT2A antagonist 19. # 2000 Elsevier Science Ltd. All rights reserved.

Description

The application of a novel solid-phase synthesis of 2,3-disubstituted indoles utilizing a carbamate indole linker is described resulting in the identi®cation of the novel, high-a nity, selective h5-HT2A antagonist 19. # 2000 Elsevier Science Ltd. All rights reserved.

Keywords

Solid-Phase Synthesis of 2,3-Disubstituted Indoles: Discovery of a Novel, High-A nity, Selective h5-HT2A Antagonist

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