A concise synthesis of 1-substituted-2-tetralones by selective diol dehydration leading to ketone transpo
Date
2012-11-20
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Dehydration of 1-substituted-1,2-tetralindiols with zinc iodide a€orded the corresponding 2-tetralones
in excellent yields. This procedure was found to be superior to the more conventional BF3-catalyzed
rearrangement of 1-substituted-1,2-epoxytetralins. # 2000 Elsevier Science Ltd. All rights reserved.
Description
Dehydration of 1-substituted-1,2-tetralindiols with zinc iodide a€orded the corresponding 2-tetralones
in excellent yields. This procedure was found to be superior to the more conventional BF3-catalyzed
rearrangement of 1-substituted-1,2-epoxytetralins. # 2000 Elsevier Science Ltd. All rights reserved.
Keywords
ketones; rearrangements; epoxides; diols.