Novel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaine
| dc.contributor.author | K. W. Bentley | |
| dc.contributor.author | G. Hardy | |
| dc.contributor.author | B. Meek | |
| dc.date.accessioned | 2012-11-20T10:29:15Z | |
| dc.date.accessioned | 2025-02-17T14:01:48Z | |
| dc.date.available | 2012-11-20T10:29:15Z | |
| dc.date.issued | 2012-11-20 | |
| dc.description | A series of secondary and tertiary alcohols have been prepared by the reduction and reaction with Grignard reagents of the aldehyde I (R = H), the ketones I (R = Me, Et, n-Pr, and Ph), and their 6,14-ethano analogs. The stereospecificity of the reactions is explained. In this way analgesics of very high potency, up to 500 times that of morphine, have been obtained | en_US |
| dc.description.abstract | A series of secondary and tertiary alcohols have been prepared by the reduction and reaction with Grignard reagents of the aldehyde I (R = H), the ketones I (R = Me, Et, n-Pr, and Ph), and their 6,14-ethano analogs. The stereospecificity of the reactions is explained. In this way analgesics of very high potency, up to 500 times that of morphine, have been obtained | en_US |
| dc.identifier.uri | https://dl.ftveti.edu.et/handle/123456789/4178 | |
| dc.language.iso | en | en_US |
| dc.subject | Novel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaine | en_US |
| dc.title | Novel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaine | en_US |
| dc.type | Article | en_US |
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