Novel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaine

dc.contributor.authorK. W. Bentley
dc.contributor.authorG. Hardy
dc.contributor.authorB. Meek
dc.date.accessioned2012-11-20T10:29:15Z
dc.date.accessioned2025-02-17T14:01:48Z
dc.date.available2012-11-20T10:29:15Z
dc.date.issued2012-11-20
dc.descriptionA series of secondary and tertiary alcohols have been prepared by the reduction and reaction with Grignard reagents of the aldehyde I (R = H), the ketones I (R = Me, Et, n-Pr, and Ph), and their 6,14-ethano analogs. The stereospecificity of the reactions is explained. In this way analgesics of very high potency, up to 500 times that of morphine, have been obtaineden_US
dc.description.abstractA series of secondary and tertiary alcohols have been prepared by the reduction and reaction with Grignard reagents of the aldehyde I (R = H), the ketones I (R = Me, Et, n-Pr, and Ph), and their 6,14-ethano analogs. The stereospecificity of the reactions is explained. In this way analgesics of very high potency, up to 500 times that of morphine, have been obtaineden_US
dc.identifier.urihttps://dl.ftveti.edu.et/handle/123456789/4178
dc.language.isoenen_US
dc.subjectNovel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaineen_US
dc.titleNovel Analgesics and Molecular Rearrangements in the Morphine-Thebaine Group. 11.' Alcohols Derived from 6,14-endo-Etheno- and 6,14-endo-Ethanotetrahydrothebaineen_US
dc.typeArticleen_US

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