A Tandem Aldol-Grob Reaction of Ketones with Aromatic Aldehydes
Date
2012-11-20
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Abstract
Aromatic aldehydes react with ketones to produce (E)-l-aryl- 1 -alkenes via a tandem Aldol-
Grob cleavage reaction sequence. The reaction, initialed by boron trifluoride, also produces a cad~xylic
acid fragment. © 1998 Elsevier Science Ltd. All rights reserved.
Description
Aromatic aldehydes react with ketones to produce (E)-l-aryl- 1 -alkenes via a tandem Aldol-
Grob cleavage reaction sequence. The reaction, initialed by boron trifluoride, also produces a cad~xylic
acid fragment. © 1998 Elsevier Science Ltd. All rights reserved.
Keywords
AIdoi, Grob Fragmentation, Boron Trifluoride, Alkene