Selective Deprotectioa of Esters Using Magnesium and Methanol

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2012-11-20

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Abstract

The use ofmagwsium m&l iu me&no1 for tbc dcprotedioo of alkyl CSIUY is described. l%ia mild reagent also pvidu good lo cxcclimt sclaWity to cleave diffrrent calen. Tk a&x of the reactivity of this rcageal towards acyl dcavagcs war fouud to be: p-nihobmzoptr > acctntc z bcnzoscc > pivatoate z-z uitl- tamidc

Description

The use ofmagwsium m&l iu me&no1 for tbc dcprotedioo of alkyl CSIUY is described. l%ia mild reagent also pvidu good lo cxcclimt sclaWity to cleave diffrrent calen. Tk a&x of the reactivity of this rcageal towards acyl dcavagcs war fouud to be: p-nihobmzoptr > acctntc z bcnzoscc > pivatoate z-z uitl- tamidc

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Selective Deprotectioa of Esters Using Magnesium and Methanol

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