Convenient Method for the Synthesis of Chiral cx,a-Diphenyl-2-pyrrolidinemethanol
Date
2012-11-14
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Abstract
A simplified, convenient synthesis of chiral a,a-diphewl- Z-pyrrolidinemethanol
involving one step Nand G-protection of S-proline using ethylchloroforeate
followed by Grignard addition-alkaline hydrolysis WCEl/CXl$Xli)s described.
Description
A simplified, convenient synthesis of chiral a,a-diphewl- Z-pyrrolidinemethanol
involving one step Nand G-protection of S-proline using ethylchloroforeate
followed by Grignard addition-alkaline hydrolysis WCEl/CXl$Xli)s described.
Keywords
Convenient Method for the Synthesis of Chiral cx,a-Diphenyl-2-pyrrolidinemethanol